Products | Tizta

Tizta

5 ML / 10 ML

TIZTA

Replenish tears naturally.

For temporary relief from burning, irritation and discomfort in the eye, and relief from discomfort due to environmental elements such as wind, smoke, sun, dry air, air conditioning & prolonged use of computers.

Composition:

Sodium Hyaluronate BP 0.1% w/v
Stabilized Oxychloro Complex 0.01% w/v (As preservative)
Sterile Aqueous Buffered Vehicle q.s.

With Glycerin IP, Boric Acid IP, Calcium Chloride IP, Erythritol USP-NF, Levocarnitine IP, Potassium Chloride IP, Borax BP and Sodium Citrate IP.

Pharmaceutical Form:

Eye Drops

Therapeutic Indication:

For temporary relief from burning, irritation and discomfort in the eye, and relief from discomfort due to environmental elements such as wind, smoke, sun, dry air, air conditioning & prolonged use of computers.

Application & Administration:

Instill one drop at a time to eye 5–6 times daily. The dosage may be adjusted according to the patient's symptoms. As directed by the Eye Surgeon / Physician.

Contraindications:

Known hypersensitivity to active component.

Storage:

Store below 30ºC. Protect from light & moisture. Do not freeze.

Tizta eye drops rarely cause serious side effect or allergic reaction. For a few moments, vision may temporarily get blurred after instillation. Minor irritation or burning may occur temporarily.
  • Do not allow the tip to make contact with the eyes.
  • Do not use while wearing soft contact lenses.
  • Keep out of reach of children.
  • NOT FOR INJECTION. FOR EXTERNAL USE ONLY.
  • Use the solution within one month after opening the container.
Drug Interactions:

There are no known drug interactions. In co-administration with other eye medication, it should always be applied last, after an interval of at least 5 minutes.

Pregnancy & Lactation:

Reproductive studies have not demonstrated any risk. Sodium Hyaluronate has a purely physical effect on the eyes without being absorbed and hence can be used during pregnancy and lactation.

Effects on Ability to Drive:

Patients who experience blurred vision after application should not drive or use machinery until their vision has cleared.

Overdose:

There are no known reports of overdosing.

Pharmacodynamic:

Sodium Hyaluronic acid contains a highly purified specific fraction of sodium salt of hyaluronic acid produced by bacterial fermentation and is therefore free from animal proteins. Hyaluronic acid is a natural polymer, present throughout the human body and also in the structures of human eyes. Its main physical characteristic is viscoelasticity. Sodium Hyaluronic acid has high viscosity between blinks and low viscosity during blinking, ensuring efficient coating of the eye surface.
Hyaluronic acid also possesses mucoadhesive properties and the ability to entrap water, resembling tear mucus glycoprotein. This increases pre-corneal residence time and tear film break-up time, resulting in longer lubrication of the corneal surface.
The protective coating helps prevent dryness and irritation. The core mechanisms of dry eye are driven by tear hyperosmolarity and tear film instability. The hypotonic solution counteracts hyperosmolarity of altered tear fluid, thus limiting corneal damage.

Pharmacokinetic:

Due to its high molecular weight, sodium hyaluronate is not expected to pass through the conjunctiva and corneal epithelium. Following intraocular administration, the half-life (t½) for elimination from the aqueous humour was around 10.5 hrs after administration.

Presentation:

Tizta Eye Drops available in 5 ml & 10 ml pack.